The internal research advisory board advises the university management on strategic research issues, in particular on the design of the research profile and the research initiative. It is anchored as part of the quality assurance system in the corresponding partial basic regulations of the RPTU. Each member represents one profile line of the RPTU research profile.
| RPTU Profile section | Member/Deputy member |
| Sustainable development and preservation of the foundations of life | 1. Prof. Dr. Ralf Schulz |
| 2. Prof. Dr. Katharina Spraul | |
| Interactions of light, spin and matter | 1. Prof. Dr. Herwig Ott |
| 2. Prof. Dr. Michael Fleischhauer | |
| Bioanalytics, membrane and systems biology in the context of cellular adaptation strategies | 1. Prof. Dr. Zuzana Storchová |
| 2. Prof. Dr. Ekkehard Neuhaus | |
High-performance materials and -engineering for innovative products | 1. Prof. Dr.-Ing. Jan Aurich |
| 2. Prof. Dr.-Ing. Tilmann Beck | |
| Mathematical modeling, algorithms and simulation of complex systems | 1. Prof. Dr. Anita Schöbel |
| 2. Prof. Dr. Anna Hundertmark | |
| Societal and digital transformations, focus on digital transformation | 1. Prof. Dr.-Ing. Norbert Wehn |
| 2. Prof. Dr.-Ing. Hans Schotten | |
| Societal and digital transformations, focus on societal transformation | 1. Prof. Dr. Michaela Maier |
| 2. Prof. Dr. Jan Schneider | |
| Analysis and design of educational processes | 1. Prof. Dr. Alexander Kauertz |
| 2. Prof. Dr. Miriam Leuchter |